Comprehensive gene expression analysis of canine invasive urothelial bladder carcinoma by RNA-Seq

2018105 citationsJournal Articlegold Open Access

Authors

Shingo Maeda · The University of Tokyo

Hirotaka Tomiyasu · The University of Tokyo

Masaya Tsuboi · The University of Tokyo

Akiko Inoue · The University of Tokyo

Genki Ishihara

Takao Uchikai

James Chambers · The University of Tokyo

Kazuyuki Uchida ·

Abstract

Our data confirmed similarities in gene expression patterns between canine and human iUC and identified potential therapeutic targets (PTGER2, ERBB2, CCND1, Vegf, and EGFR), suggesting the value of naturally occurring canine iUC as a relevant animal model for human iUC.

Topics & Keywords

Veterinary Oncology Research Inflammatory mediators and NSAID effects Bladder and Urothelial Cancer Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Cancer

Volume 18, Issue 1, pp. 472-472

DOI: 10.1186/s12885-018-4409-3

Field-Weighted Citation Impact: 5.50