Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth

201870 citationsJournal Articlebronze Open Access

Authors

Romuald Girard · University of Chicago

Hussein A. Zeineddine · University of Chicago

Janne Koskimäki · University of Chicago

Maged D Fam · University of Chicago

Ying Cao · University of Chicago

Changbin Shi · University of Chicago

Thomas Moore ·

Abstract

This is the first study reporting a predictive association between plasma biomarkers and subsequent cerebral cavernous malformation disease clinical activity. This may be applied in clinical prognostication and stratification of cases in clinical trials.

Topics & Keywords

Vascular Malformations Diagnosis and Treatment Intracerebral and Subarachnoid Hemorrhage Research Intracranial Aneurysms: Treatment and Complications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Research

Volume 122, Issue 12, pp. 1716-1721

DOI: 10.1161/circresaha.118.312680

Field-Weighted Citation Impact: 4.25