Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury

201861 citationsJournal Article

Authors

Makoto Kurano · The University of Tokyo

Koichi Tsuneyama · Tokushima University

Yuki Morimoto · Tokushima University

Tomo Shimizu · Sekisui Medical (Japan)

Masahiro Jona · University of Tokyo Hospital

Hidetoshi Kassai · The University of Tokyo

Kazuki Nakao ·

Abstract

These results suggest that apoM possesses protective properties against LPS-induced organ injuries and could potentially be introduced as a novel therapy for the severe conditions that are consequent to sepsis.

Topics & Keywords

Sphingolipid Metabolism and Signaling Inflammasome and immune disorders Cholesterol and Lipid Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Thrombosis and Haemostasis

Volume 118, Issue 06, pp. 1021-1035

DOI: 10.1055/s-0038-1641750

Field-Weighted Citation Impact: 2.94