CADM2, as a new target of miR-10b, promotes tumor metastasis through FAK/AKT pathway in hepatocellular carcinoma

201881 citationsJournal Articlegold Open Access

Authors

Dongliang Li · Harbin Medical University

Yongjian Zhang · Third Affiliated Hospital of Harbin Medical University

He Zhang · Harbin Medical University

Chao Zhan · Harbin Medical University

Xin Li · Third Affiliated Hospital of Harbin Medical University

Ba Tu · Mudanjiang Medical University

Zini Qiu

Abstract

Our study demonstrates that miR-10b-CADM2-FAK/AKT axis plays an important role in HCC metastasis, which might be a novel potential therapeutic option for HCC treatment.

Topics & Keywords

Erythrocyte Function and Pathophysiology Cancer, Hypoxia, and Metabolism Caveolin-1 and cellular processes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Experimental & Clinical Cancer Research

Volume 37, Issue 1, pp. 46-46

DOI: 10.1186/s13046-018-0699-1

Field-Weighted Citation Impact: 6.28