Efficacy and effectiveness of high-dose versus standard-dose influenza vaccination for older adults: a systematic review and meta-analysis

2018142 citationsReviewgreen Open Access

Authors

Jason K. H. Lee · University of Toronto

Gary Lam · University of Toronto

Thomas Shin · York University

Jiyeon Kim · University of Toronto

Anish Krishnan · University of Toronto

David P. Greenberg · University of Pittsburgh

Ayman Chit ·

Abstract

Available evidence suggests HD-IIV3 is more effective than SD-IIV3 at reducing the clinical outcomes associated with influenza infection in older adults and should be considered for routine use in the 65+ population.

Topics & Keywords

Influenza Virus Research Studies Respiratory viral infections research Thermal Regulation in Medicine

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Expert Review of Vaccines

Volume 17, Issue 5, pp. 435-443

DOI: 10.1080/14760584.2018.1471989

Field-Weighted Citation Impact: 12.82