Beyond HbA1c: Comparing Glycemic Variability and Glycemic Indices in Predicting Hypoglycemia in Type 1 and Type 2 Diabetes

Assessment of glycemia should go beyond HbA1c and incorporate measures of GV and glycemic indices. %CV_SMBG in type 1 diabetes and LBGI_SMBG or a combination of HbA1c and %CV_SMBG in type 2 diabetes discriminated hypoglycemia well. In defining hypoglycemia risk using GV and glycemic indices, diabetes subtypes and data source (CGM vs. SMBG) must be considered.