Methotrexate for the Treatment of Pediatric Crohn’s Disease: A Systematic Review and Meta-analysis

201840 citationsReviewbronze Open Access

Authors

Marla C. Dubinsky · Icahn School of Medicine at Mount Sinai

Abstract

This meta-analysis demonstrated that, over 50% of pediatric Crohn's disease patients induced with methotrexate achieved clinical remission, while 12-month remission rate was only 37%. Prospective controlled interventional trials should assess treatment efficacy among patient subgroups. 10.1093/ibd/izy078_video1izy078.video15774883936001.

Topics & Keywords

Inflammatory Bowel Disease Adolescent and Pediatric Healthcare Pharmaceutical studies and practices

Publication Details

Published in: Inflammatory Bowel Diseases

Volume 24, Issue 10, pp. 2135-2141

DOI: 10.1093/ibd/izy078

Field-Weighted Citation Impact: 1.98

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Methotrexate for the Treatment of Pediatric Crohn’s Disease: A Systematic Review and Meta-analysis

Authors

Abstract

Topics & Keywords

Publication Details