Association of <i>BRAF</i> Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer

2018202 citationsJournal Articlebronze Open Access

Authors

Georgios Antonios Margonis · Johns Hopkins Medicine

Stefan Buettner · Johns Hopkins University

Nikolaos Andreatos · Johns Hopkins University

Yuhree Kim · Johns Hopkins Medicine

Doris Wagner · Medical University of Graz

Kazunari Sasaki · Cleveland Clinic

Andrea Beer ·

Abstract

The presence of the V600E BRAF mutation was associated with worse prognosis and increased risk of recurrence. The V600E mutation was not only a stronger prognostic factor than KRAS but also was the strongest prognostic determinant in the overall cohort.

Topics & Keywords

Colorectal Cancer Treatments and Studies Hepatocellular Carcinoma Treatment and Prognosis Genetic factors in colorectal cancer

Publication Details

Published in: JAMA Surgery

Volume 153, Issue 7, pp. e180996-e180996

DOI: 10.1001/jamasurg.2018.0996

Field-Weighted Citation Impact: 7.93

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Association of <i>BRAF</i> Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer

Authors

Abstract

Topics & Keywords

Publication Details