Genetic Etiology for Alcohol-Induced Cardiac Toxicity

2018295 citationsJournal Articlehybrid Open Access

Authors

James S. Ware · Imperial College London

Almudena Amor‐Salamanca · Hospital Universitario Puerta de Hierro Majadahonda

Upasana Tayal · Royal Brompton & Harefield NHS Foundation Trust

Risha Govind · King's College London

Isabel Serrano · Hospital Universitari Joan XXIII de Tarragona

Joel Salazar‐Mendiguchía · Universitat Autònoma de Barcelona

José Manuel García‐Pinilla

Abstract

TTNtv represent a prevalent genetic predisposition for ACM, and are also associated with a worse left ventricular ejection fraction in DCM patients who consume alcohol above recommended levels. Familial evaluation and genetic testing should be considered in patients presenting with ACM.

Topics & Keywords

Alcohol Consumption and Health Effects Cardiovascular Function and Risk Factors Microbial metabolism and enzyme function

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of the American College of Cardiology

Volume 71, Issue 20, pp. 2293-2302

DOI: 10.1016/j.jacc.2018.03.462

Field-Weighted Citation Impact: 19.82