Glutathione metabolism in type 2 diabetes and its relationship with microvascular complications and glycemia

2018171 citationsJournal Articlegold Open Access

Authors

Fallon Lutchmansingh · University of the West Indies System

Jean W. Hsu · Children's Nutrition Research Center at Baylor College of Medicine

Franklyn I. Bennett · University of the West Indies System

Asha Badaloo · University of the West Indies

Norma McFarlane‐Anderson · University of the West Indies System

Georgiana Gordon‐Strachan · University of the West Indies System

Rosemarie Wright‐Pascoe

Abstract

Compared to non-diabetic controls, patients with T2DM have glutathione deficiency, especially if they have microvascular complications. This is probably due to reduced synthesis and increased irreversible utilization by non-glycemic mechanisms.

Topics & Keywords

Advanced Glycation End Products research Sulfur Compounds in Biology Alcohol Consumption and Health Effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 13, Issue 6, pp. e0198626-e0198626

DOI: 10.1371/journal.pone.0198626

Field-Weighted Citation Impact: 10.70