Macimorelin as a Diagnostic Test for Adult GH Deficiency

2018110 citationsJournal Articlebronze Open Access

Authors

José M. Garcia · University of Puget Sound

Beverly M. K. Biller · Massachusetts General Hospital

Márta Korbonits · Queen Mary University of London

Vera Popović · University of Belgrade

Anton Luger · Vienna General Hospital

Christian J. Strasburger · Charité - Universitätsmedizin Berlin

Philippe Chanson

Abstract

Oral macimorelin is a simple, well-tolerated, reproducible, and safe diagnostic test for AGHD with accuracy comparable to that of the ITT. A GH cutoff of 5.1 ng/mL for the macimorelin test provides an excellent balance between sensitivity and specificity.

Topics & Keywords

Growth Hormone and Insulin-like Growth Factors Genetic Syndromes and Imprinting Lipid metabolism and disorders

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 103, Issue 8, pp. 3083-3093

DOI: 10.1210/jc.2018-00665

Field-Weighted Citation Impact: 7.64

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Macimorelin as a Diagnostic Test for Adult GH Deficiency

Authors

Abstract

Topics & Keywords

Publication Details