Circulating Vitamin D and Colorectal Cancer Risk: An International Pooling Project of 17 Cohorts

2018282 citationsJournal Article

Authors

Marjorie L. McCullough · American Cancer Society

Emilie S. Zoltick · Brigham and Women's Hospital

Stephanie J. Weinstein · National Institutes of Health

Veronika Fedirko · Emory University

Molin Wang · Cancer Research And Biostatistics

Nancy R. Cook · Brigham and Women's Hospital

A. Heather Eliassen

Abstract

Higher circulating 25(OH)D was related to a statistically significant, substantially lower colorectal cancer risk in women and non-statistically significant lower risk in men. Optimal 25(OH)D concentrations for colorectal cancer risk reduction, 75-100 nmol/L, appear higher than current IOM recommendations.

Topics & Keywords

Vitamin D Research Studies Bone health and osteoporosis research Diet and metabolism studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 111, Issue 2, pp. 158-169

DOI: 10.1093/jnci/djy087

Field-Weighted Citation Impact: 24.44