Production of amphiregulin and recovery from influenza is greater in males than females

201854 citationsJournal Articlegold Open Access

Authors

Meghan S. Vermillion · Johns Hopkins University

Rebecca L. Ursin · Johns Hopkins University

Denise I. T. Kuok · HKU-Pasteur Research Pole

Landon G. vom Steeg · Johns Hopkins University

Nicholas Wohlgemuth · Johns Hopkins University

O. Hall · Johns Hopkins University

Ashley L. Fink

Abstract

Taken together, these data show that elevated levels of testosterone and AREG, either independently or in combination, improve resilience (i.e., repair and recovery of damaged tissue) and contribute to better influenza outcomes in males compared with females.

Topics & Keywords

Immune Cell Function and Interaction Respiratory viral infections research IL-33, ST2, and ILC Pathways

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Biology of Sex Differences

Volume 9, Issue 1, pp. 24-24

DOI: 10.1186/s13293-018-0184-8

Field-Weighted Citation Impact: 3.00