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Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

2018690 citationsJournal Articlebronze Open Access

Authors

Benjamin D. Hopkins · Weill Cornell Medicine

Chantal Pauli · Weill Cornell Medicine

Xing Du · NewYork–Presbyterian Hospital

Diana G. Wang · Cornell University

Xiang Li · Cornell University

David Wu · Weill Cornell Medicine

Solomon Amadiume ·

Topics & Keywords

Metabolism, Diabetes, and Cancer PI3K/AKT/mTOR signaling in cancer Pancreatic function and diabetes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nature

Volume 560, Issue 7719, pp. 499-503

DOI: 10.1038/s41586-018-0343-4

Field-Weighted Citation Impact: 27.66

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors | Researchclopedia

Weill Cornell Medicine

Marcus D. Goncalves · Weill Cornell Medicine

Cindy Hodakoski · Cornell University

Mark R. Lundquist · Cornell University

Rohan Bareja · Cornell University

Yan Ma · Columbia University Irving Medical Center

Emily Harris · Columbia University Irving Medical Center

Andrea Sboner · NewYork–Presbyterian Hospital

Himisha Beltran · Cornell University

Mark A. Rubin · New York Hospital Queens

Siddhartha Mukherjee · Columbia University Irving Medical Center

Lewis C. Cantley · Cornell University