Metabolic reprogramming-based characterization of circulating tumor cells in prostate cancer

201887 citationsJournal Articlegold Open Access

Authors

Jing Chen · Nanfang Hospital

Shunwang Cao · Southern Medical University

Bo Situ · Southern Medical University

Juan Zhong · First People's Hospital of Nanning

Yan‐Wei Hu · Southern Medical University

Shufen Li · Southern Medical University

Jinlan Huang ·

Abstract

The metabolic marker (PGK1/G6PD) is determined as the indicator for the biofunctional activity analysis of CTCs, compared with the existing morphological (EMT) classification on CTCs. The metabolic characterization of CTCs demonstrates that hypermetabolic GM<sup>+</sup>CTCs are promising biomarkers for prostate cancer metastasis.

Topics & Keywords

Cancer Cells and Metastasis Cancer, Hypoxia, and Metabolism 3D Printing in Biomedical Research

UN Sustainable Development Goals

Peace, Justice and strong institutions

Publication Details

Published in: Journal of Experimental & Clinical Cancer Research

Volume 37, Issue 1, pp. 127-127

DOI: 10.1186/s13046-018-0789-0

Field-Weighted Citation Impact: 2.83