PTENα regulates mitophagy and maintains mitochondrial quality control

201874 citationsJournal Articlebronze Open Access

Authors

Guoliang Li · Peking University

Jingyi Yang · Peking University

Chunyuan Yang · Center for Life Sciences

Minglu Zhu · Peking University

Yan Jin · Center for Life Sciences

Michael A. McNutt · Peking University

Yuxin Yin · Peking University

Abstract

BECN1 beclin 1; CCCP carbonyl cyanide m-chlorophenylhydrazone; FBXO7 F-box protein 7; FS fraction shortening; HSPA1L heat shock protein family A (Hsp70) member 1 like; HW: BW heart weight:body weight ratio; I-R ischemia-reperfusion; ISO isoprenaline; MAP1LC3/LC3 microtubule associated protein 1 light chain 3; MBH membrane binding helix; MFN1 mitofusin 1; MFN2 mitofusin 2; Nam nicotinamide; TMRM tetramethylrhodamine ethyl ester; WGA wheat germ agglutinin.

Topics & Keywords

PI3K/AKT/mTOR signaling in cancer Mitochondrial Function and Pathology Metabolism, Diabetes, and Cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Autophagy

Volume 14, Issue 10, pp. 1742-1760

DOI: 10.1080/15548627.2018.1489477

Field-Weighted Citation Impact: 3.26