Regenerative Potential of Neonatal Porcine Hearts

2018255 citationsJournal Articlebronze Open Access

Authors

Wuqiang Zhu · ZTE (United States)

Éric Zhang · ZTE (United States)

Meng Zhao · ZTE (United States)

Zechen Chong · University of Alabama at Birmingham

Chengming Fan · ZTE (United States)

Yawen Tang · ZTE (United States)

Jervaughn D. Hunter ·

Abstract

The neonatal porcine heart is capable of regeneration after AMI during the first 2 days of life. This phenomenon is associated with induction of cardiomyocyte proliferation and is lost when cardiomyocytes exit the cell cycle shortly after birth.

Topics & Keywords

Congenital heart defects research Congenital Heart Disease Studies Tissue Engineering and Regenerative Medicine

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 138, Issue 24, pp. 2809-2816

DOI: 10.1161/circulationaha.118.034886

Field-Weighted Citation Impact: 9.73