Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

A Phase 3 Trial of <scp>l</scp> -Glutamine in Sickle Cell Disease | Researchclopedia

Back to research

A Phase 3 Trial of <scp>l</scp> -Glutamine in Sickle Cell Disease

2018533 citationsJournal Articlebronze Open Access

Authors

Yutaka Niihara · University of California, Los Angeles

Scott T. Miller · State University of New York

Julie Kanter · Medical University of South Carolina

Sophie Lanzkron · Johns Hopkins Hospital

Wally R. Smith · Virginia Commonwealth University

Lewis L. Hsu · University of Illinois Chicago

Victor R. Gordeuk

Abstract

Oxidative stress contributes to the complex pathophysiology of sickle cell disease. Oral therapy with pharmaceutical

Topics & Keywords

Hemoglobinopathies and Related Disorders Metabolism and Genetic Disorders Neonatal Health and Biochemistry

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 379, Issue 3, pp. 226-235

DOI: 10.1056/nejmoa1715971

Field-Weighted Citation Impact: 31.15

· University of Illinois Chicago

Kusum Viswanathan · Brookdale University Hospital and Medical Center

Sharada A. Sarnaik · Children's Hospital of Michigan

Ifeyinwa Osunkwo · Carolinas Healthcare System

Edouard Guillaume · Interfaith Medical Center

Swayam Sadanandan · Brooklyn Hospital Center

Lance Sieger · Kaiser Permanente

Joseph L. Lasky · The Lundquist Institute

Eduard H. Panosyan · The Lundquist Institute

Osbourne A. Blake · Kaiser Permanente

Tamara New · Emory University

Rita Bellevue · NewYork–Presbyterian Brooklyn Methodist Hospital

Rafael L. Razon

Charles W. Stark · University of Southern California

Lynne Neumayr · UCSF Benioff Children's Hospital

Elliott Vichinsky · UCSF Benioff Children's Hospital