Prediction of 492 human protein kinase substrate specificities

201185 citationsJournal Articlegold Open Access

Authors

Javad Safaei · University of British Columbia

Ján Maňuch · University of British Columbia

Arvind Gupta · University of British Columbia

Ladislav Stacho · Simon Fraser University

Steven Pelech · University of British Columbia

Abstract

Application of this improved kinase substrate prediction algorithm to the primary structures of over 23, 000 proteins encoded by the human genome has permitted the identification of about 650, 000 putative phosphosites, which are posted on the open source PhosphoNET website (http://www.phosphonet.ca).

Topics & Keywords

Bioinformatics and Genomic Networks Computational Drug Discovery Methods Protein Structure and Dynamics

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Proteome Science

Volume 9, Issue Suppl 1, pp. S6-S6

DOI: 10.1186/1477-5956-9-s1-s6

Field-Weighted Citation Impact: 0.80