Epilepsy Surgery in the First 3 Years of Life: Predictors of Seizure Freedom and Cognitive Development

2018102 citationsJournal Article

Authors

Navah Ester Kadish · Goethe University Frankfurt

Thomas Bast · Goethe University Frankfurt

Gitta Reuner · Goethe University Frankfurt

Kathrin Wagner · Goethe University Frankfurt

H. Mayer · Goethe University Frankfurt

Susanne Schubert‐Bast · Goethe University Frankfurt

Gert Wiegand

Abstract

Our study demonstrates that epilepsy surgery in very young children is safe as well as efficient regarding long-term seizure freedom and antiepileptic drug cessation in selected candidates. Longer epilepsy duration is the only modifiable predictor of impaired adaptive and cognitive development, thus supporting early surgical intervention.

Topics & Keywords

Epilepsy research and treatment Pharmacological Effects and Toxicity Studies Neonatal and fetal brain pathology

UN Sustainable Development Goals

Peace, Justice and strong institutions

Publication Details

Published in: Neurosurgery

Volume 84, Issue 6, pp. E368-E377

DOI: 10.1093/neuros/nyy376

Field-Weighted Citation Impact: 5.04