Inherited Breast Cancer in Nigerian Women

2018126 citationsJournal Articlehybrid Open Access

Authors

Yonglan Zheng · Instituto Federal do Sul de Minas

Tom Walsh · Instituto Federal do Sul de Minas

Süleyman Gülsüner · Instituto Federal do Sul de Minas

Silvia Casadei · Instituto Federal do Sul de Minas

Ming K. Lee · Instituto Federal do Sul de Minas

Temidayo O. Ogundiran · Instituto Federal do Sul de Minas

Adeyinka Ademola

Abstract

Among Nigerian women, one in eight cases of invasive breast cancer is a result of inherited mutations in BRCA1, BRCA2, PALB2, or TP53, and breast cancer risks associated with these genes are extremely high. Given limited resources, prevention and early detection services should be especially focused on these highest-risk women.

Topics & Keywords

BRCA gene mutations in cancer Genetic factors in colorectal cancer Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 36, Issue 28, pp. 2820-2825

DOI: 10.1200/jco.2018.78.3977

Field-Weighted Citation Impact: 10.49