Bacterial Factors That Predict Relapse after Tuberculosis Therapy

2018153 citationsJournal Articlebronze Open Access

Authors

Roberto Colangeli · Rutgers New Jersey Medical School

Hannah Jedrey · Rutgers New Jersey Medical School

Soyeon Kim · Rutgers, The State University of New Jersey

Roy Connell · Rutgers, The State University of New Jersey

Shuyi Ma · Infectious Disease Research Institute

Uma Deepthi Chippada Venkata · Rutgers, The State University of New Jersey

Soumitesh Chakravorty

Abstract

In pretreatment isolates of M. tuberculosis with decrements of MIC values of isoniazid or rifampin below standard resistance breakpoints, higher MIC values were associated with a greater risk of relapse than lower MIC values. (Funded by the National Institute of Allergy and Infectious Diseases.).

Topics & Keywords

Tuberculosis Research and Epidemiology Mycobacterium research and diagnosis Infectious Diseases and Tuberculosis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 379, Issue 9, pp. 823-833

DOI: 10.1056/nejmoa1715849

Field-Weighted Citation Impact: 10.53