Isoproterenol suppresses recurrent torsades de pointes in a patient with long QT syndrome type 2

Key Teaching Points•Out-of-hospital cardiac arrest can be the initial presentation of congenital long QT syndrome.•Patients with long QT syndrome type 2 presenting with torsades de pointes may respond favorably to intravenous isoproterenol, as shown in this case.•Genetic counseling and testing is an important tool in the evaluation of family members of patients with congenital long QT syndrome. •Out-of-hospital cardiac arrest can be the initial presentation of congenital long QT syndrome.•Patients with long QT syndrome type 2 presenting with torsades de pointes may respond favorably to intravenous isoproterenol, as shown in this case.•Genetic counseling and testing is an important tool in the evaluation of family members of patients with congenital long QT syndrome.