The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5

2018364 citationsJournal Articlegold Open Access

Authors

Meng Zhang · Fudan University Shanghai Cancer Center

Weiwei Weng · Shanghai Medical College of Fudan University

Qiongyan Zhang · Shanghai Medical College of Fudan University

Yong Wu · Shanghai Medical College of Fudan University

Shujuan Ni · Fudan University

Cong Tan · Fudan University

Midie Xu

Abstract

Our findings indicated that NEAT1 activated Wnt signaling to promote colorectal cancer progression and metastasis. The NEAT1/DDX5/Wnt/β-catenin axis could be a potential therapeutic target of pharmacological strategies.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Hematology & Oncology

Volume 11, Issue 1, pp. 113-113

DOI: 10.1186/s13045-018-0656-7

Field-Weighted Citation Impact: 10.08