A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

201878 citationsJournal Articlegold Open Access

Authors

Juliana B. T. Carnielli · Wellcome Centre for Molecular Parasitology

Kathryn Crouch · Wellcome Centre for Molecular Parasitology

Sarah Forrester · University of York

Vladimir Costa Silva · Universidade Federal do Piauí

Sílvio Fernando Guimarães de Carvalho · Universidade Estadual de Montes Claros

Jeziel D. Damasceno · Universidade de Ribeirão Preto

Elaine Brown

Abstract

Knowledge on the presence or absence of the MSL in L. infantum will allow stratification of patients prior to treatment, helping to establish better therapeutic strategies for VL treatment. FUND: CNPq, FAPES, GCRF MRC and Wellcome Trust.

Topics & Keywords

Research on Leishmaniasis Studies Trypanosoma species research and implications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: EBioMedicine

Volume 36, pp. 83-91

DOI: 10.1016/j.ebiom.2018.09.029

Field-Weighted Citation Impact: 9.19