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Purpose of the Study Technology revolution have made the communication and information sharing quite easy and approachable around the world. Such technology platforms comes under the category of social media. However, social media bring the ease of the communication and information sharing along with negative effects on health in case of extreme usage. Especially, youngsters have encounter with negative effects of the social media platforms like bad academics performance and health (Murray et al., 2012). Therefore, increase in the number of the psychiatrist patients has occur especially of young age including college and university students. This negative effect of extreme use of social media on society cannot be ignored. Thus, current study examines the association of social media usage with depression among the collge students. Methodology The correlational study design are used and data was getheared through self administered questionnaire. Respondents were selected through simple random sampling and questionnaire were distributed to 155 students of Nisa girls college and Nursing College, Allama Iqbal Medical College through . SPSS version 21 apply the tests of frequency distribution, reliability and validiy, correlation and regression. Findings The results reveal that there exists positive and significant relationship between social media usage and depression (P<0.000) among the college students. It is the responsibility of the parents and management of educational institutes to spread the awareness and focus on the measures to avoid its extensive usage among the young adults. Significance The increase of depression among the young adults have severe damages to the society and raise the concens of the parents. This study will enhance the knowledge of parents that extreme usage of social media can cause problems of health to their childeren. Likewise, educational institutes can take the benefits of these findings to avoid such technology at their campus. Meanwhile, the policy makers of governement can take the guide while designing the regulatory policies for institutes and awareness compaigns. Future directions and limitations are provided at the end of the this study. Key Words: Social Media Usage, Depreesion, Young adults.