Search for invisible decays of a Higgs boson produced through vector boson fusion in proton-proton collisions at <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif" overflow="scroll"><mml:msqrt><mml:mrow><mml:mi>s</mml:mi></mml:mrow></mml:msqrt><mml:mo>=</mml:mo><mml:mn>13</mml:mn><mml:mspace width="0.2em"/><mml:mtext>TeV</mml:mtext></mml:math>

A search for invisible decays of a Higgs boson is performed using proton-proton collision data collected with the CMS detector at the LHC in 2016 at a center-of-mass energy s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb -1 . The search targets the production of a Higgs boson via vector boson fusion. The data are found to be in agreement with the background contributions from standard model processes. An observed (expected) upper limit of 0.33 (0.25), at 95% confidence level, is placed on the branching fraction of the Higgs boson decay to invisible particles, assuming standard model production rates and a Higgs boson mass of 125.09 GeV. Results from a combination of this analysis and other direct searches for invisible decays of the Higgs boson, performed using data collected at