Cytidine monophosphate <em>N</em>-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells

201817 citationsJournal Articlegold Open Access

Authors

Greg E. Idos · University of Southern California

Collin Hill · University of Southern California

Joan Chen · Rancho BioSciences (United States)

Abstract

Neu5Ac is selectively highly enriched in aggressive TNBC, and CMAS, the enzyme required for sialylation, may play an important role in TNBC tumor formation and invasivity.

Topics & Keywords

Glycosylation and Glycoproteins Research Cancer, Hypoxia, and Metabolism RNA modifications and cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: OncoTargets and Therapy

Volume Volume 11, pp. 6827-6838

DOI: 10.2147/ott.s177639

Field-Weighted Citation Impact: 0.65

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