Haemodynamic Mechanisms and Long-Term Prognostic Impact of Pulmonary Hypertension in Patients with Severe Aortic Stenosis Undergoing Valve Replacement

In patients with severe AS, PH is common but underlying mechanisms differ. Patients with CpcPH have higher mPAWP, lower pulmonary arterial capacitance, and worse survival than all other groups. Left atrial dysfunction and mitral regurgitation seem to be drivers of high mPAWP in CpcPH.