Carotid Plaque Rupture Is Accompanied by an Increase in the Ratio of Serum circR-284 to miR-221 Levels

2017106 citationsJournal Articlediamond Open Access

Authors

Hernan A. Bazán · Ochsner Medical Center

Samuel A. Hatfield · Ochsner Medical Center

Aaron Brug · Ochsner Medical Center

Ashton J. Brooks · Ochsner Medical Center

Daniel Lightell · Ochsner Medical Center

T. Cooper Woods · Ochsner Medical Center

Abstract

Serum circR-284:miR-221 has potential as a diagnostic biomarker of carotid plaque rupture and stroke. Moreover, we demonstrate the use of functionally related pairs of circulating noncoding RNAs as biomarkers in cardiovascular disease.

Topics & Keywords

Circular RNAs in diseases Cardiovascular Disease and Adiposity Moyamoya disease diagnosis and treatment

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Circulation Cardiovascular Genetics

Volume 10, Issue 4

DOI: 10.1161/circgenetics.117.001720

Field-Weighted Citation Impact: 4.77