The Role of TNF-α induced MSCs on Suppressive Inflammation by Increasing TGF-β and IL-10

2018111 citationsJournal Articlediamond Open Access

Authors

Agung Putra · Sultan Agung Islamic University

Fatkhan Baitul Ridwan · Sultan Agung Islamic University

Allisha Irwaniyanti Putridewi · Sultan Agung Islamic University

Azizah Retno Kustiyah · Sultan Agung Islamic University

Ken Wirastuti · Sultan Agung Islamic University

Nur Anna Chalimah Sadyah · Sultan Agung Islamic University

Ika Rosdiana

Abstract

Based on our study, we conclude that the 5 ng/mL dose of TNF-α is a sufficient dose for MSCs to suppress the inflammatory milieu. The higher increase of TGF beta is due to the controlled inflammation by IL-10.

Topics & Keywords

Mesenchymal stem cell research Electrospun Nanofibers in Biomedical Applications Wound Healing and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Open Access Macedonian Journal of Medical Sciences

Volume 6, Issue 10, pp. 1779-1783

DOI: 10.3889/oamjms.2018.404

Field-Weighted Citation Impact: 7.72