Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU

2018336 citationsJournal Articlebronze Open Access

Authors

Mette Krag · University of Copenhagen

Søren Marker · University of Copenhagen

Anders Perner · University of Copenhagen

Jørn Wetterslev · University of Copenhagen

Matt P. Wise · University Hospital of Wales

Joerg C. Schefold · University of Bern

Frederik Keus ·

Abstract

Among adult patients in the ICU who were at risk for gastrointestinal bleeding, mortality at 90 days and the number of clinically important events were similar in those assigned to pantoprazole and those assigned to placebo. (Funded by Innovation Fund Denmark and others; SUP-ICU ClinicalTrials.gov number, NCT02467621 .).

Topics & Keywords

Gastrointestinal Bleeding Diagnosis and Treatment Pneumonia and Respiratory Infections Nosocomial Infections in ICU

UN Sustainable Development Goals

Zero hungerGood health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 379, Issue 23, pp. 2199-2208

DOI: 10.1056/nejmoa1714919

Field-Weighted Citation Impact: 28.49