Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants

2018346 citationsJournal Articlehybrid Open Access

Authors

Loes C.A. Rutten‐Jacobs · University of Cambridge

Susanna C. Larsson · Karolinska Institutet

Rainer Malik · LMU Klinikum

Kristiina Rannikmäe · University of Edinburgh

Cathie Sudlow · Institute of Genetics and Cancer

Martin Dichgans · German Center for Neurodegenerative Diseases

Hugh S. Markus

Abstract

In this cohort study, genetic and lifestyle factors were independently associated with incident stroke. These results emphasise the benefit of entire populations adhering to a healthy lifestyle, independent of genetic risk.

Topics & Keywords

Genetic Associations and Epidemiology Folate and B Vitamins Research Obesity, Physical Activity, Diet

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMJ

Volume 363, pp. k4168-k4168

DOI: 10.1136/bmj.k4168

Field-Weighted Citation Impact: 13.20