The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort

2018651 citationsJournal Articlegold Open Access

Authors

Kenneth Marek · Institute for Neurodegenerative Disorders

Sohini Chowdhury · Michael J. Fox Foundation

Andrew Siderowf · University of Pennsylvania

Shirley Lasch · Institute for Neurodegenerative Disorders

Christopher S. Coffey · University of Iowa

Chelsea Caspell‐Garcia · University of Iowa

Tanya Simuni

Abstract

PPMI has detailed the biomarker signature for an early PD cohort defined by clinical features and imaging biomarkers. This strategy provides the framework to establish biomarker cohorts and to define longitudinal progression biomarkers to support future PD treatment trials.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments Neurological disorders and treatments Nuclear Receptors and Signaling

Publication Details

Published in: Annals of Clinical and Translational Neurology

Volume 5, Issue 12, pp. 1460-1477

DOI: 10.1002/acn3.644

Field-Weighted Citation Impact: 21.75

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The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort

Authors

Abstract

Topics & Keywords

Publication Details