<i>Campylobacter jejuni</i> promotes colorectal tumorigenesis through the action of cytolethal distending toxin

2018377 citationsJournal Articlehybrid Open Access

Authors

Zhen He · Sixth Affiliated Hospital of Sun Yat-sen University

Raad Z. Gharaibeh · University of Florida

Rachel C. Newsome · University of Florida

Jllian L Pope · University of Florida

Michael W. Dougherty · University of Florida

Sarah Tomkovich · Florida College

Benoît J. Pons ·

Abstract

Human clinical isolate <i>C. jejuni</i> 81-176 promotes colorectal cancer and induces changes in microbial composition and transcriptomic responses, a process dependent on CDT production.

Topics & Keywords

Salmonella and Campylobacter epidemiology Viral gastroenteritis research and epidemiology Cancer Research and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gut

Volume 68, Issue 2, pp. 289-300

DOI: 10.1136/gutjnl-2018-317200

Field-Weighted Citation Impact: 31.25