Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas

201820 citationsReviewgold Open Access

Authors

Jean Philippe Nesseler · University of California, Los Angeles

Dörthe Schaue · University of California, Los Angeles

William H. McBride · University of California, Los Angeles

Mi-Heon Lee · University of California, Los Angeles

Tania Kaprealian · University of California, Los Angeles

Simone P. Niclou · Luxembourg Institute of Health

P. Nickers

Abstract

This review aims to present the basic rationale behind this emerging complementary therapeutic approach in GBM, appraise the current preclinical and clinical data, and discuss the future challenges in improving the antitumor immune response.

Topics & Keywords

Glioma Diagnosis and Treatment Cancer Immunotherapy and Biomarkers Immune cells in cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Advances in Radiation Oncology

Volume 4, Issue 2, pp. 268-282

DOI: 10.1016/j.adro.2018.11.005

Field-Weighted Citation Impact: 1.31