A single-atom Fe–N<sub>4</sub> catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

2018271 citationsJournal Article

Authors

Wenjie Ma · Chinese Academy of Sciences

Junjie Mao · Wuhu Institute of Technology

Xiaoti Yang · Chinese Academy of Sciences

Cong Pan · Chinese Academy of Sciences

Wenxing Chen · Beijing Institute of Technology

Ming Wang · Chinese Academy of Sciences

Ping Yu ·

Abstract

Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.

Topics & Keywords

Advanced Nanomaterials in Catalysis Electrochemical sensors and biosensors Advanced biosensing and bioanalysis techniques

Publication Details

Published in: Chemical Communications

Volume 55, Issue 2, pp. 159-162

DOI: 10.1039/c8cc08116f

Field-Weighted Citation Impact: 10.02

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A single-atom Fe–N<sub>4</sub> catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

Authors

Abstract

Topics & Keywords

Publication Details