The correlation and prognostic value of serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death-ligand 1 (sPD-L1) in patients with hepatocellular carcinoma

2018123 citationsJournal Articlehybrid Open Access

Authors

Boyang Chang · Third Affiliated Hospital of Sun Yat-sen University

Tao Huang · Sun Yat-sen University Cancer Center

Huajun Wei · Gaozhou People's Hospital

Lujun Shen · Sun Yat-sen University Cancer Center

Duo Zhu · Sun Yat-sen University

Wenjun He · Sun Yat-sen University

Qifeng Chen

Abstract

Our findings indicate that sPD-1 and sPD-L1 are independent prognostic factors with opposite prognostic roles in predicting both DFS and OS in HCC patients.

Topics & Keywords

Hepatocellular Carcinoma Treatment and Prognosis Cancer Immunotherapy and Biomarkers Lung Cancer Treatments and Mutations

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer Immunology Immunotherapy

Volume 68, Issue 3, pp. 353-363

DOI: 10.1007/s00262-018-2271-4

Field-Weighted Citation Impact: 8.71