Silver sulfadiazine nanosuspension-loaded thermosensitive hydrogel as a topical antibacterial agent

201888 citationsJournal Articlegold Open Access

Authors

Xiaoya Liu · National Institutes of Pharmaceutical Research and Development (China)

Hui Gan · National Institutes of Pharmaceutical Research and Development (China)

Chaoran Hu · National Institutes of Pharmaceutical Research and Development (China)

Wenzhong Sun · National Institutes of Pharmaceutical Research and Development (China)

X. X. Zhu · National Institutes of Pharmaceutical Research and Development (China)

Zhiyun Meng · National Institutes of Pharmaceutical Research and Development (China)

Abstract

The combination of AgSD nanosuspensions and thermoresponsive hydrogel effectively improved the AgSD antibacterial activity and decreased the cytotoxicity. This study also suggested that a poloxamer thermoresponsive hydrogel could be used as a delivery system for other nanocrystals to decrease possible nanotoxicity.

Topics & Keywords

Advancements in Transdermal Drug Delivery Advanced Drug Delivery Systems Hydrogels: synthesis, properties, applications

Publication Details

Published in: International Journal of Nanomedicine

Volume Volume 14, pp. 289-300

DOI: 10.2147/ijn.s187918

Field-Weighted Citation Impact: 3.71

Command Palette

Silver sulfadiazine nanosuspension-loaded thermosensitive hydrogel as a topical antibacterial agent

Authors

Abstract

Topics & Keywords

Publication Details