Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage

2019795 citationsJournal Articlegreen Open Access

Authors

Hendrik Bartolomaeus · Max Delbrück Center

András Balogh · Max Delbrück Center

Mina Yakoub · Düsseldorf University Hospital

Susanne Homann · Düsseldorf University Hospital

Lajos Markó · Max Delbrück Center

Sascha Höges · Düsseldorf University Hospital

D Tsvetkov ·

Abstract

Our data emphasize an immune-modulatory role of SCFAs and their importance for cardiovascular health. The data suggest that lifestyle modifications leading to augmented SCFA production could be a beneficial nonpharmacological preventive strategy for patients with hypertensive cardiovascular disease.

Topics & Keywords

Metabolomics and Mass Spectrometry Studies Diet and metabolism studies Eicosanoids and Hypertension Pharmacology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 139, Issue 11, pp. 1407-1421

DOI: 10.1161/circulationaha.118.036652

Field-Weighted Citation Impact: 30.51