RETRACTED ARTICLE: Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer

2019254 citationsJournal Articlegold Open Access

Authors

Huaying Dong · Hainan General Hospital

Jianguo Hu · Dalian Medical University

Kejian Zou · Hainan General Hospital

Mulin Ye · Hainan General Hospital

Yuanwen Chen · Renji Hospital

Ching‐Yi Wu · Chongqing Medical University

Xin Chen ·

Abstract

TINCR could promote trastuzumab resistance and the accompanied EMT process in breast cancer. Therefore, TINCR might be a potential indicator for prognosis and a therapeutic target to enhance the clinical efficacy of trastuzumab treatment.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 18, Issue 1, pp. 3-3

DOI: 10.1186/s12943-018-0931-9

Field-Weighted Citation Impact: 18.28