BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

2019727 citationsJournal Articlehybrid Open Access

Authors

Andrew Lee · MRC Epidemiology Unit

Nasim Mavaddat · MRC Epidemiology Unit

Amber N. Hurson · National Cancer Institute

Alex Cunningham · MRC Epidemiology Unit

Tim Carver · MRC Epidemiology Unit

Simon Hartley · MRC Epidemiology Unit

Chantal Babb de Villiers ·

Abstract

This comprehensive model should enable high levels of BC risk stratification in the general population and women with family history, and facilitate individualized, informed decision-making on prevention therapies and screening.

Topics & Keywords

BRCA gene mutations in cancer Genetic Associations and Epidemiology Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Genetics in Medicine

Volume 21, Issue 8, pp. 1708-1718

DOI: 10.1038/s41436-018-0406-9

Field-Weighted Citation Impact: 60.13