Olanzapine Versus Placebo in Adult Outpatients With Anorexia Nervosa: A Randomized Clinical Trial

2019204 citationsJournal Articlebronze Open Access

Authors

Evelyn Attia · Cornell University

Joanna Steinglass · Cornell University

B. Timothy Walsh · Cornell University

Yuanjia Wang · Cornell University

Peng Wu · Cornell University

Colleen C. Schreyer · Cornell University

Jennifer E. Wildes ·

Abstract

This study documented a modest therapeutic effect of olanzapine compared with placebo on weight in adult outpatients with anorexia nervosa, but no significant benefit for psychological symptoms. Nevertheless, the finding on weight is notable, as achieving change in weight is notoriously challenging in this disorder.

Topics & Keywords

Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders Child Nutrition and Feeding Issues

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Psychiatry

Volume 176, Issue 6, pp. 449-456

DOI: 10.1176/appi.ajp.2018.18101125

Field-Weighted Citation Impact: 25.22