Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation

2019215 citationsJournal Article

Authors

Vishal Singh · University of Toledo

Beng San Yeoh · Pennsylvania State University

Rachel E. Walker · Pennsylvania State University

Xia Xiao · Pennsylvania State University

Piu Saha · University of Toledo

Rachel M. Golonka · University of Toledo

Jingwei Cai ·

Abstract

These results not only support the notion that fermentable fibres have the potential to ameliorate colitis but also caution that, in some contexts, prebiotic fibres can lead to gut dysbiosis and surfeit colonic butyrate that might exacerbate IBD.

Topics & Keywords

Digestive system and related health Gut microbiota and health Gastrointestinal motility and disorders

Publication Details

Published in: Gut

Volume 68, Issue 10, pp. 1801-1812

DOI: 10.1136/gutjnl-2018-316250

Field-Weighted Citation Impact: 21.86

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Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation

Authors

Abstract

Topics & Keywords

Publication Details