A simplified flow cytometric method for detection of inherited platelet disorders—A comparison to the gold standard light transmission aggregometry

The performance in microtiter plates simplified the PACT method and enabled analysis of more patients at the same time. Our results indicate that with modification of the current PACT assay, a higher negative predictive value can be obtained. Furthermore, with comparable result to LTA the PACT could be used as a screening assay for inherited platelet disorders.