Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy

201977 citationsJournal Articlebronze Open Access

Authors

Francesca Branzoli · Sorbonne Université

Clément Pontoizeau · Délégation Paris 5

Lucien Tchara · Délégation Paris 5

Anna Luisa Di Stefano · Sorbonne Université

Aurélie Kamoun · League Against Cancer

Dinesh K. Deelchand · University of Minnesota

Romain Valabrègue ·

Abstract

Our results provide strong evidence of a selective vulnerability of codeleted gliomas to serine and glutathione depletion and point to cystathionine as a possible noninvasive marker of treatment response.

Topics & Keywords

Glioma Diagnosis and Treatment Advanced MRI Techniques and Applications MRI in cancer diagnosis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neuro-Oncology

Volume 21, Issue 6, pp. 765-774

DOI: 10.1093/neuonc/noz031

Field-Weighted Citation Impact: 5.41