Once-Daily Plazomicin for Complicated Urinary Tract Infections

2019206 citationsJournal Article

Authors

Florian Wagenlehner · University of Giessen

Daniel Cloutier

Loren G. Miller · Los Angeles City College

Ian R. Friedland

Jamie P. Dwyer · Vanderbilt University Medical Center

Abstract

The increasing multidrug resistance among gram-negative uropathogens necessitates new treatments for serious infections. Plazomicin is an aminoglycoside with bactericidal activity against multidrug-resistant (including carbapenem-resistant) Enterobacteriaceae.

Topics & Keywords

Urinary Tract Infections Management Antibiotic Resistance in Bacteria Antibiotics Pharmacokinetics and Efficacy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 380, Issue 8, pp. 729-740

DOI: 10.1056/nejmoa1801467

Field-Weighted Citation Impact: 21.74