Systemic treatment for metastatic colorectal cancer in the era of precision medicine

201988 citationsReview

Authors

Jaideep Sandhu · City Of Hope National Medical Center

Abstract

The treatment of metastatic colorectal cancer has evolved over the last two decades with the FDA approval of several cytotoxic, biological, and targeted agents. In this paper, we review the impact of sidedness, RAS, BRAF, HER-2, and other immune biomarkers on metastatic colorectal cancer treatment selection and sequencing in both the palliative and curative intent settings.

Topics & Keywords

Colorectal Cancer Treatments and Studies Cancer Genomics and Diagnostics Genetic factors in colorectal cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Surgical Oncology

Volume 119, Issue 5, pp. 564-582

DOI: 10.1002/jso.25421

Field-Weighted Citation Impact: 6.27