Regulation of endothelial cell permeability by platelet-derived extracellular vesicles

201978 citationsJournal Articlegreen Open Access

Authors

Byron Miyazawa · Oregon Health & Science University

Alpa Trivedi · Oregon Health & Science University

Padma Priya Togarrati · Oregon Health & Science University

Daniel Potter · Oregon Health & Science University

Gyulnar Baimukanova · Oregon Health & Science University

Lindsay R. Vivona · Oregon Health & Science University

Maximillian Lin

Abstract

Our study is the first to report that Plt-EVs might provide a feasible product for transfusion in trauma patients to attenuate bleeding, inhibit vascular permeability, and mitigate the endotheliopathy of trauma.

Topics & Keywords

Extracellular vesicles in disease Pregnancy and preeclampsia studies Phagocytosis and Immune Regulation

Publication Details

Published in: The Journal of Trauma: Injury, Infection, and Critical Care

Volume 86, Issue 6, pp. 931-942

DOI: 10.1097/ta.0000000000002230

Field-Weighted Citation Impact: 3.68

Command Palette

Regulation of endothelial cell permeability by platelet-derived extracellular vesicles

Authors

Abstract

Topics & Keywords

Publication Details