Sinomenine mitigates collagen-induced arthritis mice by inhibiting angiogenesis

201973 citationsJournal Articlegold Open Access

Authors

Zhitao Feng · Shenzhen Zhongshan Urological Hospital

Tong Yang · China Three Gorges University

Xiaoqiang Hou · China Three Gorges University

Han-yu Wu · China Three Gorges University

Jia-teng Feng · China Three Gorges University

Bing-jin Ou · China Three Gorges University

San-Jin Cai

Abstract

SIN could mitigate CIA by inhibiting angiogenesis, and the mechanism may associate with the HIF-1α-VEGF-ANG-1 axis. Additionally, our study provides a referable experimental basis for the use of SIN for the treatment of rheumatoid arthritis.

Topics & Keywords

UN Sustainable Development Goals

Life below water

Publication Details

Published in: Biomedicine & Pharmacotherapy

Volume 113, pp. 108759-108759

DOI: 10.1016/j.biopha.2019.108759

Field-Weighted Citation Impact: 2.67